Boronic acid, B-(6-phenyl-4-dibenzofuranyl)- - Names and Identifiers
Boronic acid, B-(6-phenyl-4-dibenzofuranyl)- - Physico-chemical Properties
Molecular Formula | C18H13BO3
|
Molar Mass | 288.105 |
Density | 1.33±0.1 g/cm3(Predicted) |
Boling Point | 543.1±42.0 °C(Predicted) |
pKa | 8.00±0.30(Predicted) |
Storage Condition | -20℃ |
Boronic acid, B-(6-phenyl-4-dibenzofuranyl)- - Upstream Downstream Industry
Boronic acid, B-(6-phenyl-4-dibenzofuranyl)- - Introduction
Boronic acid, B- (6-phenyl-4-dibenzofuranyl)-is an organic compound with the chemical formula C24H17BO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1. Appearance: Boronic acid, B- (6-phenyl-4-dibenzofuranyl)-white crystalline solid.
2. Melting Point: about 250-253 degrees Celsius.
3. Solubility: low solubility in water, but soluble in organic solvents such as ethanol, dimethyl sulfoxide, etc.
Use:
Boronic acid, B- (6-phenyll-4-dibenzofuranyl)-is an important organic synthesis reagent and intermediate, widely used in organic synthesis chemistry, mainly used to construct the C- B bond of aromatic ring. It is often used in Suzuki reaction, Sonogashira Reaction, Heck reaction and other important palladium-catalyzed coupling reaction.
Method:
Boronic acid, B- (6-phenyll-4-dibenzofuranyl)-has many preparation methods, one of which is commonly used by the reaction of phenol and 2-bromodiphenol. The specific preparation steps are as follows:
1. In the presence of a base, phenol and 2-bromodiphenol are reacted in an organic solvent.
2. Adding sodium vanadium hydride (VanSchaik reaction) catalyst to continue the reaction.
3. Work up the reaction mixture to obtain the product.
4. After a series of purification steps, pure Boronic acid, B- (6-phenyl-4-dibenzofuranyl)-is obtained-.
Safety Information:
The specific security information of Boronic acid, B- (6-phenyll-4-dibenzofuranyl)-may vary depending on the usage scenarios and conditions. However, as an organic compound, the following safety precautions should generally be taken into consideration:
1. Avoid direct contact with skin, eyes and respiratory tract. During operation, it is recommended to wear appropriate personal protective equipment, such as gloves, safety glasses and protective masks.
2. During operation, pay attention to fire prevention and accumulation of electrostatic charge.
3. Storage, keep in a dry, cool, well-ventilated place, away from fire and oxidant.
4. In the use, storage and disposal process, please comply with the relevant safety procedures and regulations.
Please note that the information provided here is for reference only, and the specific nature, use, formulation and safety information need to be further determined according to the actual situation. If detailed information is required, please refer to the relevant chemical literature or consult a professional.
Last Update:2024-04-10 22:29:15